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May 14, 2026British Journal Of Nutrition

Mean Corpuscular Hemoglobin and Red Cell Distribution Width for Early Screening of Non-Anaemic Iron Deficiency in Children: A Retrospective Study

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Authors

CGChong GuoFujian Medical UniversityFZFei ZhouFujian Medical UniversityZQZhi QuMedizinische Hochschule Hannover

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Implication

Retrospective study assesses MCH and RDW for early detection of iron deficiency in children, suggesting effective screening tools.

Key Points

  • This study aims to evaluate MCH and RDW as markers for the early detection of non-anaemic iron deficiency in children.
  • Conducted a retrospective analysis of 2,018 children aged 2 months to 6 years
  • Defined iron deficiency by serum ferritin levels < 15 µg/L
  • Utilized logistic regression and ROC curve analysis for model evaluation and validation.
  • MCH was identified as an independent predictor of ID (OR = 0.63, 95% CI 0.52-0.76, p < 0.001)
  • RDW was also an independent predictor of ID (OR = 1.44, 95% CI 1.16-1.79, p = 0.001)
  • Model performance showed AUC values of 0.77 for training, 0.81 for testing, and 0.87 for validation.

Cite This Study

Guo et al. (2026) studied this question.

synapsesocial.com/papers/6a0566bda550a87e60a1eb15https://doi.org/10.1017/s0007114526107168
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