Ligand-Modulated Cobalt-Catalyzed Alkene Carbocarbonylation Unlocks Aliphatic Ketone Synthesis

, and their derivatives as the electrophiles, thus affording modular access to structurally diverse aliphatic ketones, which might find potential applications in synthetic and medicinal chemistry. Moreover, this protocol is also distinguished by its simple operation, excellent functional group compatibility, and high regio- and chemoselectivity.