Demonstrates effective dihalogenation in bicyclo[1.1.0]butane derivatives, suggesting a novel synthesis method.
A rapid catalyst-free dihalogenation/cyclization reactions of N-(2-(arylethynyl)phenyl)bicycle[1.1.0]butane-1-carboxamides and IX or NXS to assemble dihalogenated spiro[cyclobutane-1,3'-quinolin]-2'-one derivatives via strain-release reaction has been developed. The reaction features a broad substrate scope, good...
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Liu et al. (2026) studied this question.
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