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May 14, 2026European Heart Journal Acute Cardiovascular Care

Trends in the clinical profile, management and prognosis of type A aortic syndrome over the last 25 years

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Authors

ILI Arrieta LlorenteFSF Rueda SobellaIAI Julia Amill

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Overview

Randomized trial evaluates management and prognosis of type A acute aortic syndrome over 25 years, suggesting improved outcomes.

Key Points

  • This study aims to assess how the clinical profile, management strategies, and prognosis of type A acute aortic syndrome have evolved over 25 years.
  • Prospectively included 299 consecutive patients admitted to cardiac intensive care from 2000-2024 due to type A acute aortic syndrome.
  • Divided patients into 5-year periods to analyze changes in clinical, diagnostic, and therapeutic features, alongside mortality rates.
  • Used statistical analysis to compare baseline characteristics and outcomes over time.
  • Admissions due to type A acute aortic syndrome rose from 29 to 116 patients between 2000-2004 and 2020-2024.
  • In-hospital mortality decreased from 44.8% to 25.0%, with significant mortality reductions in non-operated patients (100% to 61.9%, p=0.028).
  • Lower prevalence of peripheral vascular disease (6.9% to 1.7%, p=0.044) and neurological deficits (37.0% to 11.5%, p=0.004) were noted.

Cite This Study

Llorente et al. (2026) studied this question.

synapsesocial.com/papers/6a056714a550a87e60a1f0adhttps://doi.org/10.1093/ehjacc/zuag046.253
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