Clinically circulating human bocavirus 1 underwent temporal genetic changes from 2018 to 2024, with group differentiation determined primarily by VP genes and uniquely by ORFx.
Observational
Understanding temporal genetic shifts in HBoV1 is important for enhancing the accuracy of molecular surveillance tools.
Clinically circulating HBoV1 undergoes temporal genetic change, with group differentiation determined primarily by VP genes and uniquely by ORFx at the amino acid level. These findings suggest a potential biological role for ORFx in the HBoV1 life cycle. Understanding these temporal genetic shifts is important for enhancing the accuracy of molecular surveillance tools, particularly for distinguishing genetically diverse HBoV1 strains.
Shirai et al. (Tue,) conducted a observational in Human bocavirus 1 (HBoV1). Clinically circulating human bocavirus 1 underwent temporal genetic changes from 2018 to 2024, with group differentiation determined primarily by VP genes and uniquely by ORFx.
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