PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
May 14, 2026Molecular Diversity0 citationsOpen Access

Design, synthesis, biological activity and in silico evaluation of phenylthiazole derivatives as multifunctional skin-whitening agents

YXYang XuXLXuhui LiangCHChang-Gu Hyun

Key Points

  • The aim is to design and evaluate phenylthiazole derivatives for their potential as skin-whitening agents.
  • Synthesis of phenylthiazole derivatives
  • In silico evaluation of compounds' interactions
  • Assessment of biological activity in vitro
  • Compound 3c shows the most balanced multifunctional activity among tested derivatives.
  • Topical applications of 3c demonstrate significant potential for skin-whitening effects.

Abstract

-coordinating residues and maintaining a stable energetic profile. Collectively, these findings indicate that 3c exhibits the most balanced multi-functional activity within the series and holds promise as a lead compound for topical skin-whitening applications.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/6a05684ea550a87e60a20b70https://doi.org/10.1007/s11030-026-11522-5
Ask AI
Helpful
Bookmark
Share
View Full Paper