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May 14, 2026Microchimica ActaOpen Access

Immunoaffinity biosensors for deoxynivalenol determination from wheat sample: the evaluation of antibody immobilization route and surface topography on the sensor performance

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Authors

EÖErdoğan ÖzgürSPSena PişkinCACanan Armutçu

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Overview

Randomized trial evaluates sensor performance in mycotoxin detection, suggesting effective detection strategies for food safety.

Key Points

  • This study evaluates different antibody immobilization methods and surface properties for enhanced deoxynivalenol detection.
  • Compared self-assembled monolayer (SAM) and porous poly(glycidyl methacrylate) surfaces for antibody immobilization.
  • Characterized surfaces using FTIR-ATR, AFM, CA measurements, CV, DPV, and EIS.
  • Determined deoxynivalenol in standard solutions and wheat samples with two sensor designs.
  • AuSPE/Cys@antiDON sensor had LOD of 1.43–4.33 ng/mL and LOQ of 1.67–5.07 ng/mL.
  • Recovery values for wheat sample were 103.72% and 99.76% for both sensors.
  • Sensors exhibited high selectivity, sensitivity, and repeatability for DON detection.

Cite This Study

Özgür et al. (2026) studied this question.

synapsesocial.com/papers/6a05685ca550a87e60a20db0https://doi.org/10.1007/s00604-026-08113-4
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