Dilated Cardiomyopathy and Aortic Thrombosis in a Capuchin Monkey ( Sapajus apella )

Figures

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  FIGURE 1. Gross, histopathological, and immunohistochemical findings in the myocardium. (A) Gross appearance of the heart showing a globular shape characteristic of dilated cardiomyopathy. (B) Left ventricular wall with localized reddish‐gray thinning (arrow) corresponding to the mural aneurysm detected by ultrasound. (C) Adherent thrombus in the abdominal aorta at the iliac bifurcation. (D) Low‐power view of myocardial degeneration and interstitial fibrosis in the left ventricular wall (H&E, scale bar = 200 μm); inset: Higher magnification showing cardiomyocyte shrinkage with pyknotic nuclei, myofiber loss, fibrosis, and lymphohistiocytic infiltration (scale bar = 20 μm). (E) Azan stain highlighting interstitial collagen deposition (scale bar = 200 μm); inset: Higher magnification showing marked loss of cardiomycytes with extensive fibrosis (scale bar = 20 μm). (F) Picrosirius red stain highlighting interstitial collagen deposition (scale bar = 200 μm); inset: Higher magnification showing cardiomyocyte loss with surrounding collagen‐rich fibrosis (scale bar = 20 μm). (G) Picrosirius red under polarized light showing birefringent collagen fibers (scale bar = 200 μm). (H)…