What question did this study set out to answer?

This report aims to present a successful case of treating extensive deep vein thrombosis with pharmacomechanical thrombolysis.

January 15, 2026Journal of the Society for Cardiovascular Angiography & Interventions0 citationsOpen Access

Combined, Back-to-Back Endovascular Thrombectomy for Extensive Deep Vein Thrombosis: A Case Report

PEPejmahn EftekharzadehBucks County Community College TBTalha Bhatti MWMadeeha Waleed

Key Points

This report aims to present a successful case of treating extensive deep vein thrombosis with pharmacomechanical thrombolysis.
Case report of extensive deep vein thrombosis management using pharmacomechanical thrombolysis.
Utilized two different catheter systems for treatment.
Administered a higher dose of 30 mg of tPA while avoiding bleeding complications.
Successful management of extensive deep vein thrombosis without bleeding complications.
Effective treatment achieved using back-to-back thrombolysis.
Demonstrated the feasibility of using a larger tPA dose with safer outcomes.

Abstract

Pharmacomechanical thrombolysis can aid in the management of an acute extensive deep vein thrombosis. Tissue plasminogen activator (tPA) dose varies by catheter, with the goal of avoiding bleeding by using as least amount of tPA possible. We present a case of an extensive deep vein thrombosis treated with back-to-back pharmacomechanical thrombolysis without any bleeding complications using 2 different catheter systems and a larger dose (30 mg) of tPA.

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