Key result
Increased LAVI linked to ~11% lower long-term effectiveness of thoracoscopic AF ablation.
Why the study?
The study was conducted to establish the impact of Left Atrium Volume Index on the effectiveness of thoracoscopic ablation for atrial fibrillation and define risk factors for supraventricular arrhythmias in long-term follow-up.
Does an increased Left Atrium Volume Index (LAVI) reduce the effectiveness of thoracoscopic ablation in patients with atrial fibrillation?
Cohort (n=121)
Does an increased Left Atrium Volume Index (LAVI) reduce the effectiveness of thoracoscopic ablation in patients with atrial fibrillation?
Absolute Event Rate: 77.8% vs 88.9%
Increased Left Atrium Volume Index is associated with an 11.1% reduction in the long-term effectiveness of thoracoscopic ablation for atrial fibrillation.
Research objective: establish the impact of Left Atrium Volume Index (LAVI) on on effectiveness of Thoracoscopic Ablation (TSA) in the Treatment of Atrial Fibrillation (AF) and define the risk factors for manifestation of supraventricular arrhythmias in the long-term follow-up results Methods. Prospective cohort study of 121 patients with AF (from 2018 to 2021) who performed TSA. The patients were divided into two groups: patients with increased LAVI (group I), patients with normal LAVI less than 34 ml/m 2 (group II). Results. According to echocardiography, the mean LAVI was 45.48 ± 9.3 ml/m 2 and 28.59 ± 4.13 ml/m 2 in groups I and II, respectively (p = 0.012). The mean value of left ventricular ejection fraction (LVEF) according to Teicholz in group I was 61.62 ± 7.041%, in group II 63.57 ± 6.16% (p = 0.8). Spearman's сorrelation analysis showed the relationship between LAVI and LVEF before surgery and in the long-term follow-up period, that is agreed with world literature data about contribution left atrial (LA) to left ventricular (LV) function. According to our study, only LAVI < 34 ml/m 2 is a risk factor for arrhythmia after TSA. Effectiveness TSA in I group was 77.8%, that is lower than the II group – 88.9%. 3 months after TSA, 20 (17%) patients were required catheter ablations (CA), mainly in I group. Conclusions. Research results showed that an increase in LAVI significantly reduces the effectiveness of TSA in the long-term period by 11.1% compared with LAVI < 34 ml/m 2 . That are conform with other data of previously submitted works.
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Ревишвили et al. (2022) conducted a cohort in Atrial Fibrillation (n=121). Increased Left Atrium Volume Index (LAVI ≥34 ml/m2) vs. Normal Left Atrium Volume Index (LAVI <34 ml/m2) was evaluated on Effectiveness of thoracoscopic ablation. An increased Left Atrium Volume Index (≥34 ml/m2) reduced the long-term effectiveness of thoracoscopic ablation for atrial fibrillation compared to normal LAVI (77.8% vs 88.9%).
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