Key result
Left atrioventricular coupling index ≥89% on cardiac CT strongly predicts AF recurrence post-ablation.
Why the study?
The predictive efficacy of the left atrioventricular coupling index (LACI) for atrial fibrillation recurrence after ablation remains underexplored.
Does the left atrioventricular coupling index (LACI) assessed by cardiac CT predict atrial fibrillation recurrence in patients undergoing ablation?
Cohort (n=130)
No
Does the left atrioventricular coupling index (LACI) assessed by cardiac CT predict atrial fibrillation recurrence in patients undergoing ablation?
p-value: p=< 0.001
The left atrioventricular coupling index (LACI) assessed by cardiac CT is a strong, independent predictor of atrial fibrillation recurrence after ablation, particularly when LACI is ≥ 89%.
LACI ≥89% may stratify post-ablation AF recurrence risk; leaves open prospective validation before routine use.
Background: The left atrioventricular coupling index (LACI) is a significant predictor of cardiovascular events, heart failure, and atrial fibrillation (AF). However, its predictive efficacy for AF recurrence after ablation remains underexplored. Objectives: This study aimed to evaluate the predictive value of LACI, assessed by cardiac computed tomography (CT), for AF recurrence following ablation. Methods: We performed a retrospective analysis of 130 AF patients who underwent cardiac CT before ablation at our institution from January 2019 to March 2021. LACI, defined as the ratio of left atrial to left ventricular volume during diastole, was analyzed using multivariate binary logistic regression to determine its association with AF recurrence. Kaplan-Meier survival curves assessed the duration of asymptomatic survival post-ablation. Results: < 0.001). Kaplan-Meier curves demonstrated significantly lower cumulative AF recurrence-free survival in patients with LACI ≥ 89%. Conclusion: LACI is a strong and independent predictor of AF recurrence post-ablation, offering superior risk discrimination over traditional left atrial and left ventricular parameters, thereby enhancing the clinical utility of cardiac CT before AF ablation.
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Du et al. (2026) conducted a cohort in Atrial fibrillation (n=130). Left atrioventricular coupling index (LACI) ≥ 89% vs. LACI < 89% was evaluated on Atrial fibrillation recurrence following ablation (p=< 0.001). Left atrioventricular coupling index ≥89% assessed by cardiac CT strongly predicted atrial fibrillation recurrence post-ablation, with significantly lower recurrence-free survival (P<0.001).
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