Key result
Hematocrit correction significantly alters PVR, driving massive increases in calculated resistance at higher hematocrit levels.
Why the study?
Does hematocrit correction improve the accuracy of pulmonary vascular resistance estimation in patients with anemia or polycythemia?
Population
Patients with anemia or polycythemia undergoing invasive determination of pulmonary vascular resistance
Comparison
Hematocrit correction of pulmonary vascular… vs Uncorrected PVR
Design
Review
Authors
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Hematocrit-adjusted PVR may refine PH classification in anemia or polycythemia; leaves validation and outcome impact open for prospective study.
Does hematocrit correction improve the accuracy of pulmonary vascular resistance estimation in patients with anemia or polycythemia?
Hematocrit corrections of PVR should be considered for the diagnosis and assessment of pulmonary hypertension in patients with anemia or polycythemia.
Vanderpool et al. (2018) conducted a review in Pulmonary vascular disease. Hematocrit correction of pulmonary vascular resistance was evaluated on Hematocrit-corrected pulmonary vascular resistance. Hematocrit correction of pulmonary vascular resistance significantly alters values, demonstrating that a PVR of 1.5 WU at 20% hematocrit becomes 4.1 WU at 45% and 10.8 WU at 80%.
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