Key result
Magnetic resonance imaging provides a noninvasive method for measuring coronary blood flow and flow reserve to evaluate coronary arterial stenosis, bypass graft patency, and microvascular disease.
Why the study?
Does magnetic resonance (MR) imaging allow for the noninvasive measurement of coronary blood flow and flow reserve to evaluate coronary stenosis and micro-circulation?
Does magnetic resonance (MR) imaging allow for the noninvasive measurement of coronary blood flow and flow reserve to evaluate coronary stenosis and micro-circulation?
MR imaging provides a noninvasive method to evaluate coronary blood flow, flow reserve, and myocardial micro-circulation, which is useful for detecting stenosis and assessing diffuse myocardial diseases.
May support noninvasive coronary flow research; leaves open prospective validation before clinical adoption.
The functional significance of coronary arterial stenosis can be evaluated by measuring the pharmacological flow reserve. Magnetic resonance (MR) imaging has a unique potential for noninvasive measurement of coronary blood flow and flow reserve in the native coronary artery and bypass graft. Restenosis after coronary balloon angioplasty and stenting in the left anterior descending artery can be detected noninvasively with serial MR measurements of the coronary flow reserve. Further refinement of the MR pulse sequences to improve spatial and temporal resolutions may permit accurate quantification of blood flow volume and flow reserve in all major coronary arterial branches. MR assessments of blood flow volume and flow pattern allow noninvasive detection of significant stenosis in the coronary artery bypass graft as well. By integrating MR blood flow measurement in the coronary sinus and cine MR assessment of left ventricular myocardial mass, altered myocardial micro-circulation in patients with diffuse myocardial diseases, such as hypertrophic cardiomyopathy and cardiac transplant, has been documented. J. Magn. Reson. Imaging 1999;10:728-733.
No takes yet. Share an insight, caveat, or question.
Sakuma et al. (1999) conducted a review in Coronary arterial stenosis and diffuse myocardial diseases. Magnetic resonance (MR) imaging was evaluated. Magnetic resonance imaging provides a noninvasive method for measuring coronary blood flow and flow reserve to evaluate coronary arterial stenosis, bypass graft patency, and microvascular disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: