Key result
Calcified plaque in the coronary and carotid arteries was positively associated with carotid intimal medial thickness (r=0.36 and r=0.45, respectively; both P<0.0001).
Why the study?
Is calcified arterial plaque in the coronary and carotid arteries associated with carotid intimal medial thickness?
Cross-Sectional (n=438)
Is calcified arterial plaque in the coronary and carotid arteries associated with carotid intimal medial thickness?
Effect estimate: r=0.36 (coronary), r=0.45 (carotid)
p-value: p=<0.0001
Calcified plaque in the coronary and carotid arteries measured by CT is moderately associated with carotid IMT, supporting its use as a marker of subclinical atherosclerosis.
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Calcified plaque was associated with carotid IMT; supports subclinical atherosclerosis hypothesis but leaves open incremental clinical value pending longitudinal data.
Wagenknecht et al. (2004) conducted a cross-sectional in Subclinical atherosclerosis (n=438). Coronary and carotid artery calcification vs. Carotid intimal medial thickness (IMT) was evaluated on Correlation between calcified arterial plaque and carotid IMT (r=0.36 (coronary), r=0.45 (carotid), p=<0.0001). Calcified plaque in the coronary and carotid arteries was positively associated with carotid intimal medial thickness (r=0.36 and r=0.45, respectively; both P<0.0001).
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