Impact of Uninterrupted Versus Interrupted Oral Anticoagulation on 30-Day Outcomes Following Coronary Angiography

Background: The rising prevalence of patients undergoing coronary angiography who require oral anticoagulation (OAC) presents a challenge in periprocedural management. While current North American guidelines advise OAC interruption before nonemergent coronary angiography, the impact of continuation vs interruption on outcomes remains unclear. Methods: This retrospective study included patients who underwent elective outpatient transradial coronary angiography from August 1, 2018, to March 20, 2023 at a tertiary medical center. The primary end point included 30-day outcomes of hematoma, pseudoaneurysm, perforation, arteriovenous fistula, compartment syndrome, and stroke or transient ischemic attack. No perforations, arteriovenous fistula, or compartment syndrome were observed at 30 days. Conclusions: In this institutional registry of patients who underwent elective outpatient transradial coronary angiography, an uninterrupted OAC strategy was not associated with higher rates of 30-day complications.