The value of myocardial work in the estimation of left ventricular systolic function in patients with coronary microvascular disease: A study based on adenosine stress echocardiography

Figures

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  Figure 1. Comparison of CFR between the two groups. CFR, coronary flow reserve; CMD, coronary microvascular dysfunction.

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  Figure 2. Changes in 2D-STE-related indexes and MW before and after adenosine stress in a patient in the non-CMD group. (The upper row shows 2D-STE related indices and MW at rest and the lower row shows 2D-STE related indices and MW at stress in ANOCA patient without CMD.) (This patient was a 57-year-old woman, 1.68 m tall, 65 kg, with a blood pressure of 123/80 mmHg before and 101/67 mmHg after adenosine stress, who was treated with aspirin, statin and metoprolol before examination.).

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  Figure 3. Changes in 2D-STE-related indexes and MW before and after adenosine stress in a patient in the CMD group. (The upper row shows 2D-STE related indices and MW at rest and the lower row shows 2D-STE related indices and MW at stress in ANOCA patient with CMD) (This patient was a 59-year-old woman, 1.66 m tall, 71 kg, with a blood pressure of 127/76 mmHg before and 102/64 mmHg after adenosine stress, who was treated with aspirin, statin and nicorandil before examination).

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  Figure 4. Receiver operating characteristic analysis of 2D-STE related indices, MW related indices and combined forecast metrics for predicting CMD. GLS, global longitudinal strain; PSD, peak strain dispersion; GWI, global work index; GCW, global contractive work; GWW, global waste work; GWE, global work efficiency.

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  Figure 5. Bland–Altman plots indicating intra-observer and inter-observer variabilities in 2D-STE and MW indices. The upper and lower dotted lines indicate 95% limits of agreement, while the middle dotted line indicates the zero line. The solid line represents the mean difference between the two measurements. (A) Intra-observer variability; (B) interobserver variability. GLS, global longitudinal strain; PSD, peak strain dispersion; GWI, global work index; GWW, global waste work.