Population
766 normal-weight, normotensive individuals aged 1 day to 85 years (330 female, 373 younger than 18 years)
Design
Cross-sectional
Key result
In normotensive individuals, height^2.7 was the main determinant of LV mass in children, whereas stroke work and gender were more important in adulthood, explaining 82% of variance combined.
Authors
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Age-specific LV mass indexing may improve accuracy; leaves open prognostic validation in longitudinal cohorts.
Cross-Sectional (n=766)
Effect estimate: r2=0.82
In normal-weight, normotensive individuals, body size is the main determinant of LV mass in childhood, whereas hemodynamic load and gender become more important predictors during adulthood.
Simone et al. (1998) conducted a cross-sectional in Normal-weight, normotensive individuals (n=766). Body size, stroke work, and gender was evaluated on Left ventricular (LV) mass (r2=0.82). In normotensive individuals, height^2.7 was the main determinant of LV mass in children, whereas stroke work and gender were more important in adulthood, explaining 82% of variance combined.