Key result
Mitral E/Ea correlated better with pulmonary capillary wedge pressure than BNP (r=0.69 vs r=0.32) and provided higher specificity (88% vs 56%) for predicting PCWP >15 mm Hg in ICU patients.
Why the study?
Does mitral E/Ea or BNP better predict PCWP >15 mm Hg in intensive care patients?
Observational (n=50)
Does mitral E/Ea or BNP better predict PCWP >15 mm Hg in intensive care patients?
Effect estimate: r=0.69 (E/Ea) vs r=0.32 (BNP)
p-value: p=<0.001
In intensive care patients, mitral E/Ea correlates better with PCWP and is more specific than BNP for predicting elevated left ventricular filling pressures, particularly in those with cardiac disease.
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May aid noninvasive filling pressure assessment in cardiac ICU patients; hypothesis-generating pending prospective validation.
Dokainish et al. (2004) conducted an observational in Intensive care unit patients (n=50). Mitral E/Ea vs. B-type natriuretic peptide (BNP) was evaluated on Correlation with pulmonary capillary wedge pressure (PCWP) and prediction of PCWP >15 mm Hg (r=0.69 (E/Ea) vs r=0.32 (BNP), p=<0.001). Mitral E/Ea correlated better with pulmonary capillary wedge pressure than BNP (r=0.69 vs r=0.32) and provided higher specificity (88% vs 56%) for predicting PCWP >15 mm Hg in ICU patients.
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