Why the study?
Does dabigatran and aspirin combination therapy improve thrombus dissolution in patients with thrombosis on a left atrial appendage occluder device?
Does dabigatran and aspirin combination therapy improve thrombus dissolution in patients with thrombosis on a left atrial appendage occluder device?
Combination therapy with dabigatran and aspirin may be an effective strategy for dissolving thrombus on a left atrial appendage occluder device.
Hypothesis-generating for dabigatran-aspirin in LAA occluder thrombus; controlled trials needed before adoption.
: A huge thrombus, developing after percutaneous left atrial appendage occlusion, has been successfully treated with dabigatran and aspirin as combination therapy.Although novel oral anticoagulants alone may be effective in thrombus dissolution, the association of an antiplatelet drug may safely enhance this process.
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Ciconte et al. (2017) studied this question.
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