November 1, 2005Expert Review of Cardiovascular Therapy
Transcatheter occlusion of the left atrial appendage for stroke prevention
Key result
Percutaneous occlusion of the left atrial appendage is feasible and safe, and appears to reduce the risk of stroke in atrial fibrillation patients with contraindications to long-term warfarin.
Why the study?
Does percutaneous occlusion of the left atrial appendage prevent stroke in patients with atrial fibrillation and contraindication for long-term warfarin treatment?
Population
Patients with atrial fibrillation and contraindication for long-term warfarin treatment
Design
Review
Authors
Discussion
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Overview
Supports LAA occlusion consideration in warfarin-contraindicated AF; leaves open need for randomized confirmation of stroke reduction.
Structured PICO
Does percutaneous occlusion of the left atrial appendage prevent stroke in patients with atrial fibrillation and contraindication for long-term warfarin treatment?
P
Population
Patients with atrial fibrillation and contraindication for long-term warfarin treatment
I
Intervention
Percutaneous occlusion of the left atrial appendage (using PLAATO system, WATCHMAN filter system, or Amplatzer septal occluder)
O
Outcome
Strokehard clinical
Transcatheter left atrial appendage occlusion is a feasible and safe approach for stroke prevention in patients with atrial fibrillation who are contraindicated for long-term warfarin therapy.
Cite This Study
Bayard et al. (2005) conducted a review in Atrial fibrillation. Percutaneous occlusion of the left atrial appendage was evaluated on Stroke. Percutaneous occlusion of the left atrial appendage is feasible and safe, and appears to reduce the risk of stroke in atrial fibrillation patients with contraindications to long-term warfarin.