Key result
Comprehensive review outlines the pathophysiology, novel thermodilution diagnostics, and treatments for ANOCA and INOCA.
Why the study?
Despite recent progress in understanding ANOCA and INOCA, several gaps in knowledge remain regarding these conditions.
This review provides a comprehensive overview of the pathophysiology, diagnostic innovations, and treatment modalities for patients with ANOCA and INOCA.
May guide evaluation of suspected ANOCA/INOCA; leaves open prospective validation of thermodilution techniques and targeted therapies.
A considerable number of patients with angina or myocardial ischemia have no significant coronary artery disease on invasive angiography. In recent years, several steps towards a better comprehension of the pathophysiology of these conditions, angina or ischemia with non-obstructive coronary arteries (ANOCA/INOCA) have been made. Nevertheless, several gaps in knowledge still remain. This review is intended to provide a comprehensive overview of ANOCA and INOCA with a particular focus on pathophysiology, recent diagnostic innovations, gaps in knowledge and treatment modalities.
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Maurina et al. (2023) conducted a review in Angina or ischemia with non-obstructive coronary arteries (ANOCA/INOCA). Bolus and continuous thermodilution methods was evaluated. This review provides a comprehensive overview of the pathophysiology, diagnostic innovations including bolus and continuous thermodilution, and treatments for ANOCA and INOCA.
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