February 18, 2009Current Opinion in Cardiology
Utility of B-natriuretic peptide in the evaluation of left ventricular diastolic function and diastolic heart failure
Key result
B-natriuretic peptide (BNP) levels correlate with echocardiographic parameters of diastolic dysfunction and provide diagnostic and prognostic utility in patients with diastolic heart failure.
Why the study?
Does B-natriuretic peptide (BNP) measurement provide diagnostic and prognostic utility in patients with diastolic dysfunction and diastolic heart failure?
Population
Patients with symptomatic and asymptomatic diastolic dysfunction or diastolic heart failure
Design
Review
Authors
Discussion
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Member takes
Implication
BNP may aid diastolic HF evaluation with echocardiography; leaves open need for prospective validation before routine use.
Key Points
- The aim is to evaluate the utility of B-natriuretic peptide in diagnosing and prognosticating diastolic heart failure.
- Review current literature examining the relationship between serum BNP levels and echocardiographic parameters of diastolic dysfunction.
- Discuss newer echocardiographic modalities like tissue Doppler imaging and their connection to BNP levels.
- Significant correlations exist between echocardiographic measures of diastolic dysfunction and serum BNP levels.
- BNP levels are prognostic for in-hospital mortality and hospital readmission in diastolic heart failure patients.
Structured PICO
Does B-natriuretic peptide (BNP) measurement provide diagnostic and prognostic utility in patients with diastolic dysfunction and diastolic heart failure?
P
Population
Patients with symptomatic and asymptomatic diastolic dysfunction or diastolic heart failure
I
Intervention
B-natriuretic peptide (BNP) measurement
O
Outcome
Diagnostic and prognostic utility of BNP for diastolic dysfunction and heart failure
BNP measurement, especially when combined with echocardiography, is a useful diagnostic and prognostic tool in the evaluation of diastolic heart failure.
Cite This Study
Parekh et al. (2009) conducted a review in Left ventricular diastolic function and diastolic heart failure. B-natriuretic peptide (BNP) evaluation was evaluated. B-natriuretic peptide (BNP) levels correlate with echocardiographic parameters of diastolic dysfunction and provide diagnostic and prognostic utility in patients with diastolic heart failure.