The aim is to develop conjugated polymer nanoparticles with optimized surface charge for effective dual-mode photoinactivation of resistant bacteria and biofilms.
Engineering surface charge of conjugated polymer nanoparticles
Evaluating photoinactivation and photothermal therapy (PDI-PTT) efficacy
Assessing performance metrics including η values
Achieved an η of 0.23 for dual PDI-PTT action in a single nanoparticle system
Demonstrated effective inactivation of resistant bacteria and biofilms
Significantly enhanced treatment potential through surface charge modifications
Abstract
of 0.23 and an η of 0.95 for dual PDI-PTT action) have not previously been achieved simultaneously in a single nanoparticle system.
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Sosa-Lochedino et al. (2026) studied this question.