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This research investigates how dietary α-ketoglutarate (AKG) affects broiler growth, gut health, and biochemical parameters.

May 15, 2026Veterinary SciencesOpen Access

Effect of Dietary α-Ketoglutarate Supplementation on the Performance, Gut Health, Gene Expression, Antioxidant Capacity, and Hematology in Broilers

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Randomized trial evaluates growth, gut health, and blood indicators in broilers with AKG supplementation, suggesting health benefits.

This research investigates how dietary α-ketoglutarate (AKG) affects broiler growth, gut health, and biochemical parameters.
216 one-day-old broilers randomly assigned to three groups with different AKG levels (0%, 0.5%, 1.0%)
Each group had six replicates of twelve chicks
Growth and health measures were analyzed after the supplementation period.
0.5% and 1% AKG significantly improved body weight (BW), body weight gain (BWG), and feed conversion ratio (FCR) (p < 0.05)
AKG increased total protein (TP) and albumin, while decreasing malondialdehyde (MDA) and raising catalase (CAT) concentrations
AKG improved red blood cell (RBC) and hemoglobin (Hb) levels, indicated reduced inflammation by raising IL-10 and lowering IL-1β.

Elashry et al. (2026) studied this question.

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