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This work aims to assess the clinical utility of 1,5-AG for short-term monitoring and risk evaluation of diabetes complications.

1,5-Anhydroglucitol: From Short-Term Glycemic Monitoring to Risk Stratification of Diabetes Complications

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This work aims to assess the clinical utility of 1,5-AG for short-term monitoring and risk evaluation of diabetes complications.
Reviewed literature on 1,5-AG's association with various diabetes complications.
Discussed salivary 1,5-AG measurement methods and compliance advantages.
Explored the potential optimization of detection methods.
1,5-AG correlates with multiple diabetes complications including nephropathy and retinopathy.
Non-invasive salivary measurements enhance patient compliance for glycemic monitoring.
Clinical applications of 1,5-AG are promising, though detection methods require further enhancement.

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Review evaluates 1,5-AG's role in monitoring glycemia and assessing diabetes complication risks, suggesting clinical applications.

Xu et al. (2026) studied this question.

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