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May 15, 2026Journal of Toxicology and Environmental Health0 citations

Argan and olive oils differentially modulate oxidative stress in the brain, heart, kidney, and liver of LIPOPOLYSACCHARIDE (LPS)-treated mice

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ZEZakaria EjjaltiSRSoufiane RabbaaYLYassir Laaziouez

Key Points

  • This research aims to explore how argan and olive oils affect oxidative stress in different organs of LPS-treated mice.
  • Mice were treated with lipopolysaccharide (LPS) to induce oxidative stress.
  • Argan oil (AO) and olive oil (OO) were administered to assess their effects on antioxidant capacity.
  • Tissue responses in the brain, heart, kidney, and liver were evaluated.
  • Argan oil showed greater antioxidant capacity than olive oil in all tested tissues.
  • Tissue-specific mechanisms were identified, emphasizing the role of peroxisomes in oxidative stress modulation.
  • Findings support argan oil as a promising approach to mitigate sepsis-related organ dysfunction.

Abstract

antioxidant capacity than OO. Data show importance of tissue-specific and peroxisome-associated mechanisms in modulating oxidative stress responses and support AO as a promising nutritional strategy for attenuating sepsis-related organ dysfunction.

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Cite This Study

Ejjalti et al. (2026) studied this question.

synapsesocial.com/papers/6a06b8dfe7dec685947ab661https://doi.org/10.1080/15287394.2026.2668523
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