Hypertension and dyslipidemia in women with PCOS: a population-based multiregister study in Sweden

April 1, 2026Human ReproductionOpen Access

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Key Points

The study aims to assess the impact of PCOS and its hyperandrogenic phenotype on hypertension and dyslipidemia risks.
Nationwide cohort study with 297,215 women, including 50,969 with PCOS and matched controls.
Followed participants for up to 20 years using multiple Swedish registers.
Cox regression analyses adjusted for confounding variables such as birth period and education.
Women with PCOS showed a higher risk of hypertension (aHR 2.25, 95% CI: 2.13-2.39).
Those with HA-PCOS had a significantly increased risk of hypertension (aHR 5.51, 95% CI: 4.97-6.10).
PCOS was linked to a higher risk of dyslipidemia (aHR 3.05, 95% CI: 2.69-3.46) with HA-PCOS exhibiting an even higher risk (aHR 7.82, 95% CI: 6.34-9.64).

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Evaluates hypertension and dyslipidemia risks in women with PCOS, indicating the need for early assessment.

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Persson et al. (2026) studied this question.

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