Relationships Between Antihypertensive, Glucose‐ and Lipid‐Lowering Medication Adherence, and Demographic and Clinical Characteristics in American Indian Adults With Type 2 Diabetes

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This research examines how medication adherence relates to demographic and clinical characteristics among American Indian adults with Type 2 diabetes.
Constructed a cross-sectional cohort of 3042 adults based on tribal electronic health record data.
Included adults aged ≥ 18 years with Type 2 diabetes receiving antihypertensive, glucose-, and lipid-lowering medications in 2018.
Used proportion of days covered (PDC) to assess medication adherence, considering ≥ 80% as adherent.
63% of the cohort were adherent to medications, with a mean PDC of 0.81 ± 0.18.
Adherence was greater in patients aged > 55 years (84% vs. 77%, p < 0.001).
Higher PDC was associated with BMI ≥ 30 and comorbid conditions, while insulin use and rural residence correlated with lower adherence.

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Cross-sectional study analyzes medication adherence in American Indian adults with Type 2 diabetes, suggesting key factors influencing adherence.

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Scarton et al. (2026) studied this question.

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