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A group of 20 children was assessed for possible effects at school age of prenatal exposure to methadone. Compared to a control group of 20 nonexposed children on measures of cognitive, social, and emotional development, and of achievement, no significant differences were found on cognitive tests, although methadone exposure was associated with lower IQ scores. Methadone-exposed children exhibited greater anxiety, aggression, and rejection than did those in the control group, and their mothers reported more behavior problems.
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Cubas et al. (1993) studied this question.
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