Key result
Negative stressful life events are more prevalent in bipolar patients compared with age-matched controls, and depressed bipolar subjects reported more SLE in the previous 12 months than manic subjects.
Why the study?
Are negative stressful life events more prevalent in older bipolar patients compared to younger bipolar patients and older controls?
Observational
Are negative stressful life events more prevalent in older bipolar patients compared to younger bipolar patients and older controls?
Negative stressful life events are highly prevalent in bipolar patients across age groups and are particularly associated with the depressed state.
Answers are grounded in this paper and cite their sources.
Negative SLEs associate with bipolar disorder and depression across ages; cross-sectional data leaves open causality and prospective validation needs.
OBJECTIVE: Theories about the impact of stressful life events (SLE) in bipolar disorder have focused on their role early in the disease. Few studies have examined SLE in older bipolar patients. We wanted to assess the impact of SLE in late life bipolar disorder METHODS: We evaluated negative SLE experienced by older bipolar subjects compared with younger bipolar subjects and older controls for number, type, and their association with phase of illness, age of onset, and previous episodes. RESULTS: Both younger and older bipolar subjects have more SLE than similarly aged controls. There was no significant difference in the number of stressors that younger and older bipolar subjects experienced, based on mood state, previous episodes, or age-of-onset. Both older and younger depressed bipolar subjects reported more SLE in the previous 12 months compared with those in a manic state. CONCLUSIONS: Negative SLE are much more prevalent in bipolar patients compared with age-matched controls, and continue to be frequent in later life.
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Beyer et al. (2008) conducted an observational in Bipolar disorder. Stressful life events (SLE) vs. Age-matched controls was evaluated on Number and type of negative stressful life events. Negative stressful life events are more prevalent in bipolar patients compared with age-matched controls, and depressed bipolar subjects reported more SLE in the previous 12 months than manic subjects.
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