Key result
Silent cerebral infarction was observed in 51.4% of patients with presenile-onset presenile depression (P<0.01 vs juvenile-onset) and 93.7% of those with senile-onset depression.
Why the study?
What is the incidence of silent cerebral infarction in patients with presenile or senile major depression?
Population
Patients with presenile and senile major depression diagnosed at Hiroshima Prefectural Hospital using…
Design
Cross-sectional
Authors
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Supports vascular etiology in late-onset depression; hypothesis-generating and should not yet change practice.
Cross-Sectional
No
What is the incidence of silent cerebral infarction in patients with presenile or senile major depression?
p-value: p=< .01
A high incidence of silent cerebral infarction is observed in patients with presenile- and senile-onset major depression, suggesting a potential organic etiology for late-onset depression.
Fujikawa et al. (1993) conducted a cross-sectional in Major depression. Presenile-onset presenile depression vs. Juvenile-onset presenile depression was evaluated on Silent cerebral infarction detected by MRI (p=< .01). Silent cerebral infarction was observed in 51.4% of patients with presenile-onset presenile depression (P<0.01 vs juvenile-onset) and 93.7% of those with senile-onset depression.
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