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Examines how gut microbes impact immune cells in early life, suggesting implications for disease susceptibility later.
cells brought about by alterations in early gut microbiota persist into adulthood and are associated with increased susceptibility to experimental colitis. Our studies identify a pathway of communication between intestinal microbes and thymic lymphocytes in the neonatal period that can modulate host susceptibility to immune-mediated diseases later in life.
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Ennamorati et al. (2020) studied this question.
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