Key result
Intensive BP treatment shows no cardiovascular benefit over standard care in orthostatic hypertension.
Why the study?
Does intensive blood pressure control reduce cardiovascular outcomes in patients with orthostatic hypertension?
Observational
Does intensive blood pressure control reduce cardiovascular outcomes in patients with orthostatic hypertension?
Intensive blood pressure control may not reduce cardiovascular outcomes in patients with orthostatic hypertension, highlighting a potential subgroup where intensive targets are less beneficial.
Answers are grounded in this paper and cite their sources.
May not support intensive BP targets in orthostatic hypertension; hypothesis-generating for subgroup-specific strategies.
<0.0001). Orthostatic hypertension was associated with a higher risk of cardiovascular outcomes in the intensive and not in the standard treatment group; intensive treatment of BP did not reduce the risk of cardiovascular outcomes compared with standard treatment in patients with orthostatic hypertension. These post hoc analyses are hypothesis generating and will need to be confirmed in future studies.
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Rahman et al. (2020) conducted an observational in Orthostatic hypertension. Intensive treatment of BP vs. Standard treatment was evaluated on Cardiovascular outcomes (p=<0.0001). Intensive blood pressure treatment did not reduce the risk of cardiovascular outcomes compared with standard treatment in patients with orthostatic hypertension.
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