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August 5, 1997Proceedings of the National Academy of SciencesOpen Access

A point mutation in the γ 2 subunit of γ-aminobutyric acid type A receptors results in altered benzodiazepine binding site specificity

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Authors

ABAndreas BuhrYpsomed (Switzerland)ESErwin SigelUniversity of Bern

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Buhr et al. (1997) studied this question.

synapsesocial.com/papers/6a06ef1c05e809827fd3ca55https://doi.org/10.1073/pnas.94.16.8824
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Subtle Changes in Residue 77 of the γ Subunit of α1β2γ2 GABAA Receptors Drastically Alter the Affinity for Ligands of the Benzodiazepine Binding Site1997 · 129 citations
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  4. 4Properties of single sodium channels translated by Xenopus oocytes after injection with messenger ribonucleic acid.1987 · 149 citations
  5. 5A gamma-aminobutyric acid/benzodiazepine receptor complex of bovine cerebral cortex.1983 · 368 citations