Key result
HEART score ≤3 is linked to 0% 30-day major cardiovascular events, supporting safe discharge without provocative testing.
Why the study?
Does a HEART score ≤3 identify patients with possible AMI who are at low risk for 30-day MACE and can be safely discharged without provocative testing?
Observational (n=838)
No
Does a HEART score ≤3 identify patients with possible AMI who are at low risk for 30-day MACE and can be safely discharged without provocative testing?
Answers are grounded in this paper and cite their sources.
Patients evaluated for possible AMI with a HEART score ≤3 are at extremely low risk for 30-day MACE and may be safely discharged without provocative testing.
The evaluation of individuals with possible acute myocardial infarction (AMI) is time consuming and costly. Risk stratification early during an acute care encounter presents an opportunity for increased delivery of high-value care. We sought to evaluate if the HEART score could be used in the triage of low-risk versus high-risk patients directly home without cardiac testing. Retrospective review of 838 patients placed in an observation unit for evaluation of AMI was done at a single-center, tertiary care teaching hospital. Primary outcome was major adverse cardiac event-death, AMI, or revascularization-at 30 days from the index encounter. Participants' average age was 60.1 years, 40% were male, and 67% were African American. Complete data were available for all 838 patients, including 30-day follow-up at study completion. The primary endpoint was met in 14 patients (1.7%), all of whom were in the high-risk group, with HEART score ≥4. Of the low-risk patients, 8 (2.8%) had a positive functional study, 5 underwent subsequent coronary angiography, with none (0%) found to have obstructive coronary disease. In conclusion, our results suggest that patients with a HEART score ≤3 being evaluated for chest pain are at extremely low risk for major adverse cardiac events and may be safely discharged without provocative testing. Positive cardiac testing in this population is more likely to represent a false-positive finding, resulting in unnecessary testing. These findings should be prospectively validated.
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Michaels et al. (2018) conducted an observational in possible acute myocardial infarction (AMI) (n=838). HEART score ≤3 (low-risk) vs. HEART score ≥4 (high-risk) was evaluated on major adverse cardiac event (death, AMI, or revascularization) at 30 days. Patients with a HEART score ≤3 evaluated for possible AMI had a 0% rate of 30-day major adverse cardiac events, suggesting they can be safely discharged without provocative testing.
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