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January 1, 1997American Journal of Respiratory and Critical Care Medicine

Cigarette Smoking: A Risk Factor for Idiopathic Pulmonary Fibrosis

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Authors

KBKathy B. BaumgartnerUniversity of LouisvilleJSJames M. SametUniversity of North Carolina at Chapel HillCSChristine A. StidleyUniversity of New Mexico

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Implication

Randomized trial examines smoking's link to idiopathic pulmonary fibrosis, suggesting increased risk with recent cessation.

Key Points

  • The aim is to investigate the association between smoking and the risk of developing idiopathic pulmonary fibrosis (IPF).
  • Multicenter case-control design involving 248 IPF cases and 491 matched control subjects.
  • Telephone interviews gathered data on smoking history and other potential risk factors.
  • Conditional logistic regression analyzed the association between smoking and IPF risk.
  • Cases had a higher history of ever smoking (72%) compared to controls (63%).
  • The odds ratio for ever smoking was 1.6 (95% CI: 1.1 to 2.4).
  • Elevated risk for former smokers (OR = 1.9; 95% CI: 1.3 to 2.9) and smokers with 21 to 40 pack-years (OR = 2.3; 95% CI: 1.3 to 3.8).

Cite This Study

Baumgartner et al. (1997) studied this question.

synapsesocial.com/papers/6a07676b2edded7c7b843710https://doi.org/10.1164/ajrccm.155.1.9001319
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