Key result
Vein graft surgery for severe coronary artery disease was associated with a lower annual attrition rate (4.8% per year) compared to a historical nonsurgical cohort (9.3% per year).
Why the study?
Does vein graft surgery improve survival and symptoms in patients with severe coronary artery disease compared to no surgical treatment?
Population
1,469 patients with severe coronary artery disease/obstructions
Comparison
Myocardial revascularization with vein graft… vs No surgical treatment
Design
Cohort
Follow-up
22 to 60 months
Authors
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Should not yet change practice in severe CAD; leaves open confirmation of benefit in randomized trials.
Cohort (n=1,469)
Does vein graft surgery improve survival and symptoms in patients with severe coronary artery disease compared to no surgical treatment?
Absolute Event Rate: 4.8% vs 9.3%
Vein graft surgery for severe coronary artery disease is associated with improved long-term survival and symptom remission compared to non-surgical management.
Sheldon et al. (1973) conducted a cohort in Severe coronary artery disease (n=1,469). Vein graft surgery vs. No surgical treatment (historical cohort) was evaluated on Annual rate of attrition (mortality). Vein graft surgery for severe coronary artery disease was associated with a lower annual attrition rate (4.8% per year) compared to a historical nonsurgical cohort (9.3% per year).
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