Key result
A novel 31-kD PDZ-motif protein, ZASP, was identified, showing specific expression in heart and skeletal muscle and localization in the sarcomere at the Z-band level.
Population
Heart and skeletal muscle tissue
Design
Preclinical
Authors
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May guide sarcomere protein research in muscle; leaves open clinical relevance in human disease.
Identifies ZASP, a novel PDZ-motif protein in the sarcomere Z-band of heart and skeletal muscle, which may play a role in multiprotein complex organization.
Faulkner et al. (1999) studied Skeletal and heart muscle protein characterization. ZASP identification and characterization was evaluated. A novel 31-kD PDZ-motif protein, ZASP, was identified, showing specific expression in heart and skeletal muscle and localization in the sarcomere at the Z-band level.
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