Combining cryoballoon pulmonary vein isolation with superior vena cava ablation did not enhance freedom from atrial tachyarrhythmia at 12 months compared to PVI alone (P=0.91).
RCT (n=100)
randomly assigned
Does combining cryoballoon pulmonary vein isolation with superior vena cava ablation improve freedom from atrial tachyarrhythmia in patients with paroxysmal or non-long-standing persistent atrial fibrillation?
Routine inclusion of superior vena cava ablation during first-time cryoballoon pulmonary vein isolation for atrial fibrillation does not improve arrhythmia-free survival and increases complications.
p-value: p==0.91
BACKGROUND: Superior vena cava (SVC) has been considered a specific trigger in atrial fibrillation development. METHODS: We investigated the efficacy and safety of combining cryoballoon pulmonary vein isolation (PVI) with SVC ablation compared with PVI alone in 100 patients with paroxysmal or non-long-standing persistent atrial fibrillation. Patients were randomly assigned to either the PVI+SVC ablation group or the PVI-only group. Each patient was given a mobile device to record a daily ECG and detect atrial tachyarrhythmias. RESULTS: =0.91). CONCLUSIONS: The addition of SVC ablation to PVI did not enhance freedom from atrial tachyarrhythmia at 12 months, and it led to increased complications. These findings do not support the routine inclusion of SVC ablation in cryoballoon procedures for first-time catheter ablation in patients with paroxysmal or non-long-standing persistent atrial fibrillation.
Castro‐Urda et al. (Mon,) conducted a rct in paroxysmal or non-long-standing persistent atrial fibrillation (n=100). Cryoballoon pulmonary vein isolation (PVI) with SVC ablation vs. PVI alone was evaluated on Freedom from atrial tachyarrhythmia (p==0.91). Combining cryoballoon pulmonary vein isolation with superior vena cava ablation did not enhance freedom from atrial tachyarrhythmia at 12 months compared to PVI alone (P=0.91).