What is the clinical evidence from this study?

Population: Cardioinhibitory vasovagal syncope (n=11). Intervention: Short AV delay VDD pacing vs. Without pacing. Primary outcome: Positive vasovagal outcomes during tilt test.

What question did this study set out to answer?

The study aims to determine if short AV delay VDD pacing can prevent vasovagal syncope during tilt testing in patients with cardioinhibitory vasovagal syndrome.

May 1, 1994Pacing and Clinical Electrophysiology

Short AV Interval VDD Pacing Does Not Prevent Tilt Induced Vasovagal Syncope in Patients with Cardioinhihitory Vasovagal Syndrome

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Key result

Short AV delay VDD pacing did not prevent tilt-induced vasovagal syncope compared to no pacing, with positive vasovagal outcomes occurring in 82% of paced tilts versus 64% of unpaced tilts.

Why the study?

Does short AV delay VDD pacing prevent tilt induced vasovagal syncope in patients with cardioinhibitory vasovagal syndrome?

Population

11 subjects who had previously received permanent dual chamber pacemakers for cardioinhibitory vasovagal…

Comparison

Short AV delay VDD pacing during Westminster… vs Without pacing during Westminster protocol tilt…

Design

Cohort

Authors

MPMARK E.V. PETERSENGloucestershire Royal Hospital DPDenise PriceMoseley Hall Hospital TWTim WilliamsUniversity of Hohenheim

Discussion

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Implication

Short AV delay VDD pacing should not yet be adopted for vasovagal syncope prevention; leaves open the efficacy of other pacing approaches in cardioinhibitory cases.

Key Points

The study aims to determine if short AV delay VDD pacing can prevent vasovagal syncope during tilt testing in patients with cardioinhibitory vasovagal syndrome.
Eleven subjects with dual chamber pacemakers underwent tilt tests with and without short AV delay VDD pacing.
Each subject underwent paired Westminster protocol tilt tests to compare outcomes between paced and unpaced conditions.
82% of paced tilts resulted in positive vasovagal outcomes compared to 64% of unpaced tilts.
No significant differences in heart rate or blood pressure behavior were observed between the two conditions.
A trend towards accelerated syncope occurrence was noted during paced tilts for subjects with positive outcomes (P=0.054).

Structured PICO

Does short AV delay VDD pacing prevent tilt induced vasovagal syncope in patients with cardioinhibitory vasovagal syndrome?

Population

11 subjects (mean age 50 years, range 33-71 years) who had previously received permanent dual chamber pacemakers for cardioinhibitory vasovagal syncope

Intervention

Short AV delay VDD pacing during Westminster protocol tilt test

Comparator

Without pacing during Westminster protocol tilt test

Outcome

Positive vasovagal outcomes during tilt testsurrogate

Main Result

Absolute Event Rate: 82% vs 64%

Atrial synchronous ventricular pacing (short AV interval VDD) does not prevent the initiation or progression of tilt-induced vasovagal syncope in predisposed subjects.

Cite This Study

PETERSEN et al. (1994) studied Cardioinhibitory vasovagal syncope (n=11). Short AV delay VDD pacing vs. Without pacing was evaluated on Positive vasovagal outcomes during tilt test. Short AV delay VDD pacing did not prevent tilt-induced vasovagal syncope compared to no pacing, with positive vasovagal outcomes occurring in 82% of paced tilts versus 64% of unpaced tilts.

synapsesocial.com/papers/6a07b4b015d371b38838685d https://doi.org/10.1111/j.1540-8159.1994.tb01429.x

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Implication

Short AV delay VDD pacing should not yet be adopted for vasovagal syncope prevention; leaves open the efficacy of other pacing approaches in cardioinhibitory cases.

Short AV Interval VDD Pacing Does Not Prevent Tilt Induced Vasovagal Syncope in Patients with Cardioinhihitory Vasovagal Syndrome

Discussion

Member takes

Implication

Key Points

Structured PICO

Main Result

Cite This Study

Short AV Interval VDD Pacing Does Not Prevent Tilt Induced Vasovagal Syncope in Patients with Cardioinhihitory Vasovagal Syndrome

Discussion

Member takes

Implication

Key Points

Structured PICO

Main Result

Cite This Study

Also Consider

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