Key result
Review details the genetics, clinical features, and treatments of heritable potassium channel arrhythmias.
Design
Review
Authors
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Alerts clinicians to potassium channel mutation patterns in arrhythmias; leaves open mutation-specific therapy trials.
This review summarizes the diversity and functional roles of cardiac potassium channels and how their heritable mutations lead to distinct arrhythmias like long and short QT syndromes.
Crotti et al. (2020) conducted a review in Heritable arrhythmias (long and short QT syndromes, atrial fibrillation, J-wave syndromes). This review summarizes the genetic basis, clinical manifestations, and therapeutic approaches for heritable arrhythmias caused by mutations in cardiac potassium channels.
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