Race and Ethnic Disparities in Stroke Incidence in the Northern Manhattan Study
Why the study?
Data on stroke incidence disparities related to Hispanic ethnicity remain limited, despite established excess stroke incidence among blacks versus whites.
Do race and ethnic disparities affect stroke incidence in a multiethnic elderly population?
Population
3298 multiethnic participants in NOMAS
Comparison
Blacks and Hispanics vs whites
Design
Prospective population-based cohort study
Follow-up
Mean of 14±7 years
Authors
Discussion
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Implication
Black adults retain excess stroke risk after SES adjustment; confirms disparities in multiethnic cohorts but leaves mechanisms and interventions open.
Key Points
- This study aims to assess race and ethnic disparities in stroke incidence among a multiethnic population in Northern Manhattan.
- Analyzed data from the prospective Northern Manhattan Study (NOMAS) with a mean follow-up of 14 years.
- Utilized multivariable-adjusted Cox proportional hazards models to estimate associations between race/ethnicity and stroke incidence.
- Stratified analyses were conducted by age to evaluate variations in disparities.
- Overall, blacks had a higher stroke risk compared to whites (HR 1.51, 95% CI, 1.13-2.02).
- Hispanics exhibited an increased stroke rate compared to whites (age/sex-adjusted HR 1.48, 95% CI, 1.13-1.93).
- The disparity persisted for Hispanic women aged ≥70, even after adjusting for socioeconomic factors (HR 1.17, 95% CI, 0.85-1.62).
Structured PICO
Do race and ethnic disparities affect stroke incidence in a multiethnic elderly population?
P
Population
3,298 participants in the prospective population-based Northern Manhattan Study (NOMAS), mean baseline age 69±10 years, 37% men, 24% black, 21% white, 52% Hispanic.
O
Outcome
Incident stroke of any subtype and ischemic strokehard clinical
Black and Hispanic populations have a higher incidence of stroke compared to whites, with the disparity in Hispanics largely driven by socioeconomic factors.
Cite This Study
Gardener et al. (2020) studied this question.