Key result
Novel nomogram predicts LAT or SEC in NVAF with ~0.84 C-index, outperforming standard risk scores.
Why the study?
Does a nomogram predict left atrial thrombus or spontaneous echo contrast in patients with non-valvular atrial fibrillation?
Cohort (n=1,813)
No
Does a nomogram predict left atrial thrombus or spontaneous echo contrast in patients with non-valvular atrial fibrillation?
A newly constructed nomogram incorporating six clinical characteristics may help predict the presence of left atrial thrombus or spontaneous echo contrast in patients with non-valvular atrial fibrillation.
May aid thrombus risk stratification in non-valvular AF; leaves open external validation before clinical adoption.
In this study, a nomogram was constructed that incorporated six characteristics of NVAF patients. The nomogram may be of great value for the prediction of LAT/SEC in NVAF patients.
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Li et al. (2021) conducted a cohort in Non-valvular atrial fibrillation (n=1,813). Nomogram (incorporating age, LAD, LVEF, HTN, previous stroke/TIA, and non-paroxysmal AF) vs. CHADS2 and CHA2DS2-VASc scores was evaluated on Prediction of Left Atrial Thrombus (LAT) or Spontaneous Echo Contrast (SEC) (C-index/AUC). A novel nomogram incorporating six clinical and echocardiographic variables predicted left atrial thrombus or spontaneous echo contrast in non-valvular atrial fibrillation with a C-index of 0.836, outperforming standard risk scores.
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