INTRODUCTION ... . . . . . . . . . . . .. . ...... . . . . . . ......... ... ....... . .. . ...... . . . . . .. . .. 187 HISTORICAL PERSPECTiVE 188 CONCEPTUAL ISSUES 189 METHODOLOGY ... .... .... ..... .. 190 MECHANISM OF UPTAKE 190 Initial Uptake. . . . . . . . . . . . . .. . . . . . . . . . . . .. . .... . . . . . . . . . . . . . . . . . . . . .. . ... . . . . . . . . . . . . . . . . . . . . . . . . . . . 191 Role of Vitamin Metabolism . . . . . . . . . . . . .. ......... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193 Cellular Disposition . . . . . . . . . . . . . . .. . . .. .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193 CONCLUSION ....... ........ 194
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Bowman et al. (1989) studied this question.
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