Key result
Post-AMI recovery improves reduced LVEF in ~55% of patients within a month, with minimal further gains.
Why the study?
Does left ventricular ejection fraction improve sufficiently within 1 month after acute myocardial infarction to remove the indication for an implantable cardioverter-defibrillator?
Population
100 patients admitted for acute myocardial infarction (AMI) with reduced LVEF (≤40%)
Design
Cohort
Follow-up
3 months
Authors
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Should not yet alter post-AMI ICD timing; leaves open optimal reassessment in prospective trials.
Cohort (n=100)
Does left ventricular ejection fraction improve sufficiently within 1 month after acute myocardial infarction to remove the indication for an implantable cardioverter-defibrillator?
The majority of LVEF improvement after AMI occurs within the first month, suggesting that waiting beyond this period for ICD implantation may not be necessary and leaves patients exposed to a high risk of life-threatening arrhythmias.
Sjöblom et al. (2014) conducted a cohort in Acute Myocardial Infarction with reduced LVEF (n=100). Echocardiographic follow-up was evaluated on Proportion of patients with LVEF >35%. Post-AMI recovery over 1 month resulted in 55% of patients with initial LVEF ≤40% improving their LVEF to >35%, with minimal further improvement (1.9 percentage units) over the next 2 months.
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