Key result
Left ventricular long-axis changes in early diastole strongly correlated with systolic function (adjusted r2=0.70 for amplitude), indicating that isolated diastolic dysfunction is uncommon.
Population
311 subjects aged 20-89 years with variable degrees of systolic function and diastolic function
Design
Cross-sectional
Authors
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May question isolated diastolic dysfunction diagnoses in practice; leaves open validation in longitudinal outcome studies.
Observational (n=311)
Effect estimate: r2=0.70
Ventricular long-axis changes in early diastole are closely related to systolic function, suggesting that 'pure' or isolated diastolic dysfunction is uncommon.
Yip et al. (2002) conducted an observational in Variable systolic and diastolic function (n=311). Tissue Doppler and M-mode echocardiography was evaluated on Correlation between systolic and diastolic long-axis changes (mitral annular amplitude and peak velocity) (r2=0.70). Left ventricular long-axis changes in early diastole strongly correlated with systolic function (adjusted r2=0.70 for amplitude), indicating that isolated diastolic dysfunction is uncommon.
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