Key result
The ACTN3 gene is proposed as a possible marker for muscle skeletal injury susceptibility, as enhanced muscle strength ability may act as a protective factor against sports training-induced injuries.
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May support ACTN3 genotyping for athlete injury risk; leaves open prospective validation before any clinical adoption.
It is well known that the increasing overload imposed by physical training lead the athletes to improve athletic performance. On the other hand, these high-intensity training sessions, followed by factors such as high impact loads, also increase the injuries risk in different sites such as in the bones [1], muscle-tendon unit [2], and joints [3]. Previous findings have suggested that a high level of strength and/or power production ability could be considered one of the main factors related to prevention of the skeletal muscle injuries in sports [4,5]. In this way, it is believed that the enhanced muscle strength ability acts as a protector factor against sports training-induced injuries [6,7].
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Leonardo A. Pasqua (2014) conducted a review in Muscle Skeletal Injury Susceptibility. ACTN3 Gene was evaluated. The ACTN3 gene is proposed as a possible marker for muscle skeletal injury susceptibility, as enhanced muscle strength ability may act as a protective factor against sports training-induced injuries.
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