Key result
Prior CABG in ACS patients is linked to lower in-hospital morbidity and mortality.
Why the study?
What are the clinical outcomes and prognosis of patients with prior CABG presenting with acute coronary syndrome?
What are the clinical outcomes and prognosis of patients with prior CABG presenting with acute coronary syndrome?
Despite adverse baseline characteristics, recent evidence suggests improved in-hospital morbidity and mortality for prior CABG patients presenting with ACS over the past two decades.
Generally, patients with prior coronary artery bypass graft (CABG) are often under-represented in acute coronary syndrome (ACS) clinical trials. Nevertheless, there is growing global attention concerning their short- and long-term prognosis. Some reports suggest prior CABG as an independent risk factor for increased mortality, while others report an equal or a more favorable prognosis despite their adverse baseline clinical characteristics. The reasons for this 'risk-mortality paradox' need to be further evaluated. More recent reports showed a significant reduction in in-hospital morbidity and mortality over a 20-year period of follow up that may be attributed to the improvement in surgical CABG techniques and increased use of evidence-based therapies over the past two decades. In the current review we discuss the available literature regarding outcomes of prior CABG patients who are presenting with ACS.
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Al-Aqeedi et al. (2014) conducted a review in Acute coronary syndrome in patients with prior coronary artery bypass graft. Prior coronary artery bypass graft (CABG) was evaluated on In-hospital morbidity and mortality. Prior CABG in patients presenting with acute coronary syndrome is associated with a significant reduction in in-hospital morbidity and mortality over a 20-year period.
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