Neutrophil to lymphocyte ratio was independently associated with the severity of coronary artery disease as assessed by the SYNTAX score (coefficient β 0.380) in patients with NSTEMI.
Cross-Sectional (n=449)
No
Is the neutrophil to lymphocyte ratio associated with the severity of coronary artery disease (SYNTAX score) in patients with NSTEMI?
Higher neutrophil to lymphocyte ratio at presentation is independently associated with greater angiographic severity of coronary artery disease in patients with NSTEMI.
Effect estimate: coefficient β 0.380 (95% CI 1.165-1.917)
p-value: p=<0.001
In this study we aimed to investigate whether there is an association between the neutrophil to lymphocyte ratio (NLR) and severity of coronary artery disease (CAD) in patients with non-ST segment elevation myocardial infarction (NSTEMI) using the SYNTAX score (SXscore). A total of 414 patients with NSTEMI who underwent coronary angiography were enrolled in the study. NLR was measured for all patients at presentation. The study population was then divided into 3 tertiles based on the SYNTAX trial results.(1)) The low syntax group (n = 329) was defined as those with an SXscore ≤ 22, the intermediate syntax group (n = 58) was defined as an SXscore ≥ 23 and < 33, and the high syntax group (n = 27) as those with an SXscore ≥ 33. NLR was significantly lower in patients with a low SXscore compared to patients with an intermediate SXscore or high SXscore (3.7 ± 4 to 4.6 ± 2 and 7.9 ± 4, P < 0.001). Linear regression analysis revealed that NLR (coefficientβ = 0.380, 95%CI: 1.165-1.917, P < 0.001) was significantly associated with the SXscore in patients with NSTEMI. Our results indicate that NLR is independently associated with the severity of CAD in patients with NSTEMI.
Kurtul et al. (Wed,) conducted a cross-sectional in Non-ST Segment Elevation Myocardial Infarction (NSTEMI) (n=449). Neutrophil to Lymphocyte Ratio (NLR) was evaluated on SYNTAX score (coefficient β 0.380, 95% CI 1.165-1.917, p=<0.001). Neutrophil to lymphocyte ratio was independently associated with the severity of coronary artery disease as assessed by the SYNTAX score (coefficient β 0.380) in patients with NSTEMI.