What question did this study set out to answer?

This research aims to analyze the effects of nutritional selection on mouse growth across generations.

February 1, 1960Genetics ResearchOpen Access

Selection of mice for growth on high and low planes of nutrition

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Randomized trial examines growth responses of mice to different nutritional conditions, suggesting selection strategies impact development.

This research aims to analyze the effects of nutritional selection on mouse growth across generations.
Two-way selection was applied to mice reared on high and low planes of nutrition over several generations.
Growth was measured for four lines of mice across both nutritional planes, estimating genetic correlations and responses.
Heritability and phenotypic variation were assessed up to seven generations to evaluate selection outcomes.
Genetic correlation estimates varied between generations, with values of 0.75, 0.19, 0.66, and 0.57 recorded.
Mice selected for growth on a low nutrition plane maintained comparable growth when later reared on a high plane but exhibited improved fat and protein composition.
The lines demonstrated differing responses and heritabilities throughout the experiment, indicating selective pressures varied.

D. S. Falconer (1960) studied this question.

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Randomized trial examines growth responses of mice to different nutritional conditions, suggesting selection strategies impact development.